Models

in vitro 

cells in culture:

  • SH-SY5Y cells
  • SY5Y-Mock cells
  • SY5Y-APP695 cells (Alzheimer model)
  • SH-SY5Y-P301 cells (Alzheimer model)
  • SY5Y-APPsw cells
  • PC12neo cells
  • PC12sw cells (Alzheimer model)
  • HEK-APPwt cells
  • HEK-APPsw cells (Alzheimer model)

ex vivo

  • human peripheral blood mononuclear cells (PBMC), isolated from volunteers and patients
  • dissociated brain cells, isolated from murine brains

in vivo

Rodents:   

  • aged NMRI mice
  • aged C57/BL6 mice


Nematodes:

  • C. elegans, N2
  • C. elegans, CL2006 (Alzheimer model)


Behaviour tests:

  • Open field
  • Passive avoidance
  • Social recognition
  • Object recognition
  • Y-maze
  • Barnes-maze
  • Rotarod
  • Nesting
  • Enriched Environment
  • Volunteer physical activity 


© Prof. Dr. Gunter P. Eckert 2018