Dr. Carmina Silaidos, M.Sc.

Carmina Schaefer

Carmina Silaidos (neé Schaefer) holds a Master of Science (M.Sc.) in nutritional science. For her Ph.D. she is currently doing research on the preventive effects of blueberry polyphenols on mitochondrial dysfunction as key factor of brain aging and Alzheimer’s disease (AD). She contributes to a close cooperation with the clinic for general medicine (Prof. Johannes Pantel, Dr. Silke Matura) and the clinic for neuroradiology (Dr. Ulrich Pilatus), Clinics-Goethe-University Frankfurt that establishes mitochondrial function in isolated lympocyts using high performace respirometry, imaging of  energy metabolites using P-MRT, and cognitive tests as a peripheral model of mitochondrial dysfunction in humans. Furhter, she establishes a cellular model mimicking the human blood brain barrier. 

Methods:   Measurement of mitochondrial membrane potential (MMP) and ATP levels, respiromentry, Western Blot, ...


  • Biomarkers in Nutrtion and Health


Silaidos C, Grube J, Muley C, Eckert GP.
Time dependent melatonin secretion is associated with mitochondrial function in peripheral blood mononuclear cells (PBMC) of male volunteers.
Mitochondrion 2020, in press (IF 3.449)

Dilberger B, Passon M, Asseburg H, Silaidos CV, Schmitt F, Schmiedl T, Schieber A, Eckert GP.
Polyphenols and Metabolites Enhance Survival in Rodents and Nematodes-Impact of Mitochondria.
Nutrients. 2019 Aug 13;11(8). pii: E1886. [
open access(IF 4.196)

Silaidos C, Pilatus U, Grewal R, Matura S, Lienerth B, Pantel J, Eckert GP.
Sex-associated differences in mitochondrial function in human peripheral blood
mononuclear cells (PBMCs) and brain. 
Biol Sex Differ. 2018 Jul 25;9(1):34. [
open access(IF 3.188)

Asseburg H, Schaefer C, Mueller M, Hagl S, Pohland M, Berressem D, Borchielline, M, Plank C, Eckert GP
Effects of grape skin extract on age-related mitochondrial dysfunction, memory and life span in C57BL/6J mice
NeuroMolecular Med, 2016, 18(3):378-95.

Presentations at conferences:

"Geschlechts-und Altersspezifische Unterschiede der mitochondrialen Funktion in peripheren mononukleären Blutzellen (PBMC) und im Gehirn“ [Gender and aged specific differences of mitochondrial function in peripheral mononuclear blood cells (PBMC) and in the brain].  Healthy Aging Conference, March 16, 2017, Fulda, Germany.

© Prof. Dr. Gunter P. Eckert 2018