Rekha Grewal, M.Sc.

Rekha Grewal

Rekha Grewal holds a Master of Science (M.Sc.) in chemistry. For her Ph.D. she is currently doing research on olive polyphenols for the prevention of dementia in frame of the BMBF-KMU project NeurOliv. For her Ph.D. studies she uses neuronal cells that model Alzheimer´s disease. The focus lies on the assessment of mitochondrial function

Methods:   Measurement of mitochondrial membrane potential (MMP) and ATP levels, respiromentry, Western Blot



Fuchs C, Bakuradze T, Steinke R, Grewal R, Eckert GP, Richling E.
Polyphenolic composition of extracts from winery by-products and effects on cellular cytotoxicity and mitochondrial functions in HepG2 cells.
J Function Food. 2020, 
accepted (IF 3.197)

Grewal R, Reutzel M, Dilberger B, Hein H,  Silaidos C, Zotzel J, Marx S, Tretzel J, Sarafeddinov A, Fuchs C,  Eckert GP.
Purified Oleocanthal and Ligstroside protect against mitochondrial dysfunction in models of early Alzheimer´s Disease and brain ageing
Exp Neurol. 2020, 328:113248.  [Pubmed Abstract(IF 4.562) 

Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP.
Effects of Long-Term Treatment with a Blend of Highly Purified Olive Secoiridoids on Cognition and Brain ATP Levels in Aged NMRI Mice.
Oxid Med Cell Longev. 2018:4070935. [
open access] (IF 4.868)

Silaidos C, Pilatus U, Grewal R, Matura S, Lienerth B, Pantel J, Eckert GP.
Sex-associated differences in mitochondrial function in human peripheral blood
mononuclear cells (PBMCs) and brain. 
Biol Sex Differ. 2018 Jul 25;9(1):34. [
open access(IF 3.188)

Stark T, Lieblein T, Pohland M, Kalden E, Freund P, Zangl R, Grewal R, Heilemann M, Eckert GP, Morgner N, Göbel MW.
Peptidomimetics That Inhibit and Partially Reverse the Aggregation of Aβ(1-42). Biochemistry. 2017; 56(36):4840-4849.  [Pubmed Abstract
(IF 2.952)

Hagl S, Berressem D, Grewal R, Grebenstein N, Frank J, Eckert GP
Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice
Nutr Neurosci, 2016, 19(1):1-10. 

Hagl S, Grewal R, Ciobanu I, Helal A, Khayyal MT, Muller WE, Eckert GP
Rice Bran Extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer's disease
J Alz Dis 2015, 1;43(3):927-38. [Pubmed Abstract]

Presentations at conferences:

"GinkoTerp verbessert die mitochondriale Funktion in PC12-Zellen.“ [GinkgoTerp improves mitochondrial functions in PC12 cells].  Healthy Aging Conference, March 16, 2017, Fulda, Germany.

© Prof. Dr. Gunter P. Eckert 2018