News

Please find here the latest news of our research group!

Funkkolleg Ernährung



hr-iNFO, die Justus-Liebig-Universität und die vhs Gießen laden ein zum Start des neuen Funkkollegs Ernährung.

Genuss – Gesundheit – Geschäft

Low Carb oder Vollkorn? Mango-Smoothie oder Streuobst-Birne? Superfood oder Schweineschnitzel? Über solche Fragen entbrennen regelrechte Glaubenskriege. Von der Biologie über Welternährung bis hin zum Einfluss der Lebensmittelindustrie – in 23 Folgen geht das hr-iNFO Funkkolleg Ernährung den Dingen auf den Grund – unterhaltsam, kritisch und auf dem neuesten Stand der Wissenschaft.


Bei der Auftaktveranstaltung zum neuen Funkkolleg gibt es jede Menge Wissen in verständlichen Häppchen. …

new Ph.D. student in the lab


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Giessen, February, 1, 2017Benjamin Dilberger holds a Master of Science (M.Sc.) in nutritional sciences. For his Ph.D. he is currently developing C. elegans as new research tool to investigate brain aging and Alzheimer`s diseases following the mitochondrial cascade hypothesis. In his collaborative project he is closely working with the reserach group of Prof. Wenzel who chaired the professorship in molecular nutrition research. 


new Ph.D. student in the lab 2


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Giessen, March 1, 2017.  Carsten Esselun holds a Master of Science (M.Sc.) in chemistry. For his Ph.D. he is currently exploring the molecular mechanisms of polyunsaturated fatty acids on the balance of n3-/n6 fatty acids and its effects on fatty acid metabolism. Further, he is doing research in frame of the project  “Effect of Walnuts on Mitochondrial Function and Cognition in a Mouse Model of Aging



11. FACS meeting

Fatty acids in cell signaling 2013

Bad Homburg, June 15.-19., 2013

The 11th Fatty Acids in Cell Signaling meeting aims at highlighting the impact of polyunsaturated fatty acids in human health throughout the whole lifespan. Renowned experts in the field will highlight emerging topics in seven age-related sessions and four plenary lectures. The 11th FACS meeting continued a series of expert meetings that greatly advanced our understanding of the role of fatty acids in human health.

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research high-lights


Rice Bran Extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer’s disease

Mitochondrial dysfunction plays an important role in brain aging and has emerged to be an early event in Alzheimer’s disease (AD), contributing to neurodegeneration and the loss of physical abilities seen in patients suffering from this disease. We examined mitochondrial dysfunction in a cell culture model of Alzheimer’s disease (PC12APPsw cells) releasing very low β-amyloid (Aβ40) levels and thus mimicking early AD stages.  Our data show that these cells have impaired energy metabolism, low ATP levels and decreased endogenous mitochondrial respiration. …

new post-doc in the lab

Stephanie Hagl has sucessfully defend her thesis and earned her Ph.D. in pharmacology. She will continue her reserach in the group and will be responsible  for the PorridgePlus-Project which is funded by the Federal Ministry of Economics (BMWi)  in frame of a ZIM-initiative (KF3204601).

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new Project - „PorridgePlus"

February 20, 2014. STUTTGART. The Federal Ministry of Economics (BMWi) supports in frame of the ZIM-initiative a project called PorridgePlus (KF3204601). The aim of the project is to develop a food product for elderly with the objective to promote healthy brain aging. The basis for the project are findings that Rice Bran Extract protects from mitochondrial dysfunction in the brain. Mitochondrial dysfunction plays a major role in the development of age-related neurodegenerative diseases and recent evidences suggest that food ingredients can improve mitochondrial function. The Kick-off meeting held in Stuttgart launches the biennial project. …

Hope for stroke patients

Intravenous Treatment with a Long-Chain Omega-3 Lipid Emulsion Provides Neuroprotection in a Murine Model of Ischemic Stroke - A Pilot Study

Single long-chain omega-3 fatty acids (e.g. docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA)) are known for their neuroprotective properties associated with ischemic stroke. This pilot study aimed to test the effectiveness of an acute treatment with a longchain omega-3 lipid emulsion (Omegaven 10%®, OGV) that contains fish oil (DHA 18 mg/ ml; EPA 21 mg/ml) and α-tocopherol (0.2 mg/ml) in a transient middle cerebral artery occlusion (MCAO) model of ischemic stroke in mice. …

Dissertation Award for Dr. Hagl


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Frankfurt, December, 10, 2014.The dissertation award of the Frankfurt Biotech Alliance honors outstanding scientific work in Life Sciences  and is awarded to candidates whose research results have implications for the economy. In 2014 Dr. Stephanie Hagl was one out of three laureates who convinced the jury with her excellent work. The ceremoney took place in the chamber of commerce in Frankfurt.  


A mushroom against neurodegeneration - new project

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Gießen, July 21, 2017 - The Horst Görtz Foundation is pleased to inform us that our proposal, “Secondary metabolites of H. erinaceus against neurodegenerative diseases” has been approved in the total amount of 150,000 €. This study aims to isolate active ingredients of H. erinaceus and test the potential of erinacines to improve mitochondrial function using different cell and animal models of Alzheimer`s disease. 

© Prof. Dr. Gunter P. Eckert 2018