Fabian Schmitt, M.Sc. 

Fabian Schmitt holds a Master of Science (M.Sc.) in nutritional sciences. For his Ph.D. he is currently working with the nematode C. elegans as a model for research in aging and Alzheimer`s diseases. In his projects he is observing the health benefits of dietary supplements produced by fermentation of fruits and vegetables. He is also investigating the impact of cofilin, the actin-binding protein, on the mitochondrial function during Alzheimer’s disease.

Methods: measurement of mitochondrial membrane potential (MMP), ATP levels, markers of mitochondrial mass; High-Resolution Respirometry (Oxygraph-2k); western blotting, qRT-PCR, heatstress assay, real-time-lifespan assay, chemotaxis assay, food-race assay, paralysis measuring.

Projects: 

  • Fermeted fruits & vegetables and its detoxifying effects after contact with environmentally hazardous substances
  • Impact of cofilin on mitochondrial function 

Publications:

Dilberger B, Passon M, Asseburg H, Silaidos CV, Schmitt F, Schmiedl T, Schieber A, Eckert GP.
Polyphenols and Metabolites Enhance Survival in Rodents and Nematodes-Impact of Mitochondria.
Nutrients. 2019 Aug 13;11(8). pii: E1886. [open access(IF 4.196)

Dilberger B, Baumanns S, Schmitt F, Schmiedl T, Hardt M, Wenzel U, Eckert GP.
Mitochondrial Oxidative Stress Impairs Energy Metabolism, Reduces Stress Resistance and Longevity of C. Elegans.
Oxid Med Cell Longev. 2019:6840540 [open access(IF 4.868)

© Prof. Dr. Gunter P. Eckert 2018